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PIK-293

Product Specifications

UNSPSC Description

PIK-293, an analog of IC87114, is a PI3K inhibitor, with IC50 values of 0.24 μM, 10 μM, 25 μM and 100 μM for p110δ, p110β, p110γ and p110α, respectively[1].

Target Antigen

PI3K

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/pik-293.html

Smiles

O=C1N(C2=CC=CC=C2C)C(CN3N=CC4=C(N)N=CN=C43)=NC5=C1C(C)=CC=C5

Molecular Weight

397.43

References & Citations

[1]Knight ZA, et al. A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling. Cell. 2006 May 19;125(4):733-47.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-13504/PIK-293-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-13504/PIK-293-SDS-MedChemExpress.pdf

CAS Number

900185-01-5

Available Sizes

Curated Selection

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