Glipizide (Standard)

Glipizide (Standard) is the analytical standard of Glipizide. This product is intended for research and analytical applications. Glipizide (CP 2872; K 4024) a potent, orally active and sulfonylurea class anti-diabetic agent and can be used for type 2 diabetes mellitus research but not type 1. Glipizide acts by partially blocking ATP-sensitive potassium (KATP) channels among β cells of pancreatic islets of Langerhans[1][2].

Product Specifications

CAS Number

[29094-61-9]

Product Name Alternative

CP 28720 (Standard) ; K 4024 (Standard)

UNSPSC

12352005

Hazard Statement

H302, H315, H320, H335

Target

Potassium Channel; Reference Standards

Type

Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Others

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/glipizide-standard.html

Purity

99.72

Smiles

O=C(C1=NC=C(C)N=C1)NCCC2=CC=C(S(=O)(NC(NC3CCCCC3)=O)=O)C=C2

Molecular Formula

C21H27N5O4S

Molecular Weight

445.54

Precautions

H302, H315, H320, H335

References & Citations

[1]B J Zünkler, et al. Concentration-dependent effects of tolbutamide, meglitinide, glipizide, glibenclamide and diazoxide on ATP-regulated K+ currents in pancreatic B-cells. Naunyn Schmiedebergs Arch Pharmacol. 1988 Feb;337 (2) :225-30.|[2]Glipizide. From Wikipedia