Rovanersen (sodium)
Rovanersen sodium is an antisense oligonucleotide that specifically targets mutated mRNA copies of the huntington (HTT) gene without affecting healthy mRNA of HTT gene, thereby preventing the production of faulty Huntingtin protein. Rovanersen sodium can be used for huntington’s disease research[1].
Product Specifications
CAS Number
2231347-41-2
Product Name Alternative
WVE-120101 (sodium)
UNSPSC
12352208
Target
Huntingtin
Type
Oligonucleotides
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rovanersen-sodium.html
Purity
95.58
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
[Rovanersen(sodium)]
Molecular Formula
C202H240N82Na19O111P19S13
Molecular Weight
6617 (free acid)
References & Citations
[1]M Meena, et al. Selectivity and Biodistribution of WVE-120101, a Potential Antisense Oligonucleotide Therapy for the Treatment of Huntington’s Disease (S56.001) . AAN Enterprises. April 18, 2017; 88 (16 Supplement) .
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
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