Borocaptate (sodium )
Product Specifications
UNSPSC Description
Borocaptate sodium is a boron-containing compound that can be used as a therapeutic agent in boron neutron capture therapy (BNCT), exhibiting anticancer activity[1][2].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/borocaptate-sodium.html
Solubility
H2O : 175 mg/mL (ultrasonic)
Smiles
SB1234[BH]567[BH]89%10[BH]%11%12%13[BH]85%14[BH]%11%15%16[BH]%12%17%18[BH]%139%19[BH]%1061[BH]%19%172[BH]%15%183[BH]%14%1674.[Na].[Na]
Molecular Weight
219.87
References & Citations
[1]Bendel P, et al. Optimal detection of the neutron capture therapy agent borocaptate sodium (BSH): A comparison between and NMR[J]. Medical Physics, 2001, 28(2): 178-183.|[2]Kraft SL, et al. Borocaptate sodium: a potential boron delivery compound for boron neutron capture therapy evaluated in dogs with spontaneous intracranial tumors. Proc Natl Acad Sci U S A. 1992 Dec 15;89(24):11973-7.|[3]Yoshida F, et al. Enhancement of sodium borocaptate (BSH) uptake by tumor cells induced by glutathione depletion and its radiobiological effect. Cancer Lett. 2004 Nov 8;215(1):61-7.|[4]Kokai-Kun J F, et al. Lysostaphin as a treatment for systemic Staphylococcus aureus infection in a mouse model[J]. Journal of antimicrobial chemotherapy, 2007, 60(5): 1051-1059.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-142041/Borocaptate-sodium-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-142041/Borocaptate-sodium-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
144885-51-8
Available Sizes
Curated Selection
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