Borocaptate (sodium)

Borocaptate sodium is a boron-containing compound that can be used as a therapeutic agent in boron neutron capture therapy (BNCT), exhibiting anticancer activity[1][2].

Product Specifications

CAS Number

[144885-51-8]

Product Name Alternative

BSH

UNSPSC

12352300

Hazard Statement

H315, H319, H335

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/borocaptate-sodium.html

Purity

95.0

Solubility

H2O : 175 mg/mL (ultrasonic)

Smiles

SB1234c567c89%10c%11%12%13c581C%11%142c%15%163c%12%17%14c%13%189c6%19%10c%1574c%17%16%18%19.C[BH].[2Na+].[2-]

Molecular Formula

B12H12Na2S

Molecular Weight

219.87

Precautions

H315, H319, H335

References & Citations

[1]Bendel P, et al. Optimal detection of the neutron capture therapy agent borocaptate sodium (BSH) : A comparison between and NMR[J]. Medical Physics, 2001, 28 (2) : 178-183.|[2]Kraft SL, et al. Borocaptate sodium: a potential boron delivery compound for boron neutron capture therapy evaluated in dogs with spontaneous intracranial tumors. Proc Natl Acad Sci U S A. 1992 Dec 15;89 (24) :11973-7.|[3]Yoshida F, et al. Enhancement of sodium borocaptate (BSH) uptake by tumor cells induced by glutathione depletion and its radiobiological effect. Cancer Lett. 2004 Nov 8;215 (1) :61-7.|[4]Kokai-Kun J F, et al. Lysostaphin as a treatment for systemic Staphylococcus aureus infection in a mouse model[J]. Journal of antimicrobial chemotherapy, 2007, 60 (5) : 1051-1059.