Borocaptate (sodium)
Borocaptate sodium is a boron-containing compound that can be used as a therapeutic agent in boron neutron capture therapy (BNCT), exhibiting anticancer activity[1][2].
Product Specifications
CAS Number
144885-51-8
Product Name Alternative
BSH
UNSPSC
12352300
Hazard Statement
H315, H319, H335
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/borocaptate-sodium.html
Purity
95.0
Solubility
H2O : 175 mg/mL (ultrasonic)
Smiles
SB1234c567c89%10c%11%12%13c581C%11%142c%15%163c%12%17%14c%13%189c6%19%10c%1574c%17%16%18%19.C[BH].[2Na+].[2-]
Molecular Formula
B12H12Na2S
Molecular Weight
219.87
Precautions
H315, H319, H335
References & Citations
[1]Bendel P, et al. Optimal detection of the neutron capture therapy agent borocaptate sodium (BSH) : A comparison between and NMR[J]. Medical Physics, 2001, 28 (2) : 178-183.|[2]Kraft SL, et al. Borocaptate sodium: a potential boron delivery compound for boron neutron capture therapy evaluated in dogs with spontaneous intracranial tumors. Proc Natl Acad Sci U S A. 1992 Dec 15;89 (24) :11973-7.|[3]Yoshida F, et al. Enhancement of sodium borocaptate (BSH) uptake by tumor cells induced by glutathione depletion and its radiobiological effect. Cancer Lett. 2004 Nov 8;215 (1) :61-7.|[4]Kokai-Kun J F, et al. Lysostaphin as a treatment for systemic Staphylococcus aureus infection in a mouse model[J]. Journal of antimicrobial chemotherapy, 2007, 60 (5) : 1051-1059.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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