ASC-69
ASC-69 (APY69) is a potent and promising PD-1/PD-L1 small-molecule inhibitor[1].
Product Specifications
CAS Number
[1216665-50-7]
Product Name Alternative
APY69
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PD-1/PD-L1
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/asc-69.html
Purity
99.63
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N#CCC1=CC=C(NC2=NC(C)=CC(NC3=NNC(C4CC4)=C3)=N2)C=C1
Molecular Formula
C19H19N7
Molecular Weight
345.40
Precautions
H302, H315, H319, H335
References & Citations
[1]Song Z, et al. Design, Synthesis, and Pharmacological Evaluation of Biaryl-Containing PD-1/PD-L1 Interaction Inhibitors Bearing a Unique Difluoromethyleneoxy Linkage. J Med Chem. 2021;64 (22) :16687-16702.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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