LBG20304
LBG20304 (compound 2s) is a ligand for the homologous GluK5 receptor (IC50: 432 nM), more than 40-fold selective over the homologous GluK1-3 isoforms. Low doses of LBG20304 (10 μM), it exhibits low agonist activity in neuronal slices (rat) [1].
Product Specifications
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lbg20304.html
Smiles
O=C([C@H]1NC[C@H](N2N=NC=C2C3=CC=C4C=C(O)C=CC4=C3)[C@@H]1CC(O)=O)O
Molecular Formula
C19H18N4O5
Molecular Weight
382.37
References & Citations
[1]Domoic Acid as a Lead for the Discovery of the First Selective Ligand for Kainate Receptor Subtype 5 (GluK5)
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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