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LBG20304

LBG20304 (compound 2s) is a ligand for the homologous GluK5 receptor (IC50: 432 nM), more than 40-fold selective over the homologous GluK1-3 isoforms. Low doses of LBG20304 (10 μM), it exhibits low agonist activity in neuronal slices (rat) [1].

Product Specifications

UNSPSC

12352005

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/lbg20304.html

Smiles

O=C([C@H]1NC[C@H](N2N=NC=C2C3=CC=C4C=C(O)C=CC4=C3)[C@@H]1CC(O)=O)O

Molecular Formula

C19H18N4O5

Molecular Weight

382.37

References & Citations

[1]Domoic Acid as a Lead for the Discovery of the First Selective Ligand for Kainate Receptor Subtype 5 (GluK5)

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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