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MPIF-1/CCL23, Human (75a.a)

MPIF-1/CCL23 protein, Human (75a.a), a CC chemokine, is highly chemotactic for resting T cells and monocytes, mediates inflammatory and immune responses by binding to the chemokine receptor CCR1, inhibits myeloid progenitor cell formation, and has some pro-cancer effects. MPIF-1/CCL23 Protein, Human (75a.a) is a recombinant human MPIF-1/CCL23 (R46-N120) protein expressed by E. coli[1].

Product Specifications

Product Name Alternative

MPIF-1/CCL23 Protein, Human (75a.a), Human, E. coli

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/mpif-1-ccl23-protein-human.html

Purity

95.0

Smiles

RFHATSADCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQVCVRMLKLDTRIKTRKN

Molecular Formula

6368 (Gene_ID) P55773-1 (R46-N120) (Accession)

Molecular Weight

Approximately 11 kDa

References & Citations

[1]A Simats, et al. CCL23: a new CC chemokine involved in human brain damage. J Intern Med. 2018 May;283 (5) :461-475.|[2]Júlia Faura, et al. CCL23: A Chemokine Associated with Progression from Mild Cognitive Impairment to Alzheimer's Disease. J Alzheimers Dis. 2020;73 (4) :1585-1595.|[3]Jan Korbecki, et al. CC Chemokines in a Tumor: A Review of Pro-Cancer and Anti-Cancer Properties of the Ligands of Receptors CCR1, CCR2, CCR3, and CCR4. Int J Mol Sci. 2020 Nov 9;21 (21) :8412.|[4]Kyu Yeon Han, et al. CCL23 up-regulates expression of KDR/Flk-1 and potentiates VEGF-induced proliferation and migration of human endothelial cells. Biochem Biophys Res Commun. 2009 Apr 24;382 (1) :124-8.|[5]Son KN, et al. Human CC chemokine CCL23 enhances expression of matrix metalloproteinase-2 and invasion of vascular endothelial cells. Biochem Biophys Res Commun. 2006 Feb 10;340 (2) :498-504.|[6]Chih-Horng Shih, et al. CCL23/myeloid progenitor inhibitory factor-1 inhibits production and release of polymorphonuclear leukocytes and monocytes from the bone marrow. Exp Hematol. 2005 Oct;33 (10) :1101-8.

Shipping Conditions

Room temperature in continental US; may vary elsewhere.

Storage Conditions

Stored at -20°C for 2 years

Scientific Category

Recombinant Proteins

Available Sizes

Frequently Asked Questions

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