SOD1 rabbit pAb
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
P00441
Swiss Prot
P00441
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from the Internal region of human SOD-1.
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF
Dilution
Western Blot: 1/500 - 1/2000.IHC-p:1:50-300. Not yet tested in other applications.
Molecular Weight
18kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
18kD
Fragment
IgG
Subcellular Location
Other Product Names
SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1
Gene ID (Human)
6647
Available Sizes
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