Sulopenem etzadroxil
Sulopenem etzadroxil is an orally active prodrug of the antibiotic Sulopenem. Sulopenem etzadroxil is active in mice infected with Bacillus anthracis[1][2][3].
Product Specifications
CAS Number
1000296-70-7
Product Name Alternative
PF-03709270
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sulopenem-etzadroxil.html
Purity
98.66
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C(N12)=C(S[C@@H](CC3)C[S@@]3=O)S[C@]2([H])[C@@H]([C@H](O)C)C1=O)OCOC(C(CC)CC)=O
Molecular Formula
C19H27NO7S3
Molecular Weight
477.62
References & Citations
[1]Bush K, et al. New β-lactam antibiotics and β-lactamase inhibitors. Expert opinion on therapeutic patents, 2010, 20 (10) : 1277-1293. |[2]Puttagunta S, et al. 1724. Murine Efficacy Studies of Sulopenem Against Bacillus anthracis[C]//Open Forum Infectious Diseases. US: Oxford University Press, 2022, 9 (Supplement_2) : ofac492. 1354. |[3]Zhanel GG, et al. Sulopenem: An Intravenous and Oral Penem for the Treatment of Urinary Tract Infections Due to Multidrug-Resistant Bacteria. Drugs. 2022 Apr;82 (5) :533-557.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
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