Porcn-IN-1
Porcn-IN-1 is potent porcupine inhibitor with an IC50 of 0.5±0.2 nM.
Product Specifications
CAS Number
[2036044-77-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Porcupine
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Porcupine-IN-1.html
Concentration
10mM
Purity
99.57
Solubility
DMSO : ≥ 100 mg/mL
Smiles
FC1=C(C2=CC(C)=NC=C2)N=CC(CNC(C3=CC=C(C(C=CC=C4)=C4N5)C5=C3)=O)=C1
Molecular Formula
C25H19FN4O
Molecular Weight
410.44
Precautions
H302, H315, H319, H335
References & Citations
[1]Xu Z, et al. Design, synthesis, and evaluation of novel porcupine inhibitors featuring a fused 3-ring system based on the 'reversed' amide scaffold.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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