E3 Ligase Ligand-linker Conjugate 139
Product Specifications
UNSPSC Description
E3 Ligase Ligand-linker Conjugate 139 is the E3 ubiquitin ligase ligand and linker of PROTAC KB03-SLF, used for research in the field of cancer[1].
Target Antigen
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e3-ligase-ligand-linker-conjugate-139.html
Smiles
O=C(C1=CC(NC(CCl)=O)=CC(C(F)(F)F)=C1)NCCC(NCCOCCOCCC(O)=O)=O
Molecular Weight
511.88
References & Citations
[1]Xiaoyu Zhang, et al. Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16. Nat Chem Biol. 2019 Jul;15(7):737-746.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-169969/E3-Ligase-Ligand-linker-Conjugate-139-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-169969/
Clinical Information
No Development Reported
CAS Number
2375197-04-7
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