Pomolic acid

Randialic acid A (Pomolic acid) is a pentacyclic triterpene isolated from Euscaphis japonica (Tunb.) . Randialic acid A (Pomolic acid) inhibits tumor cells growth and induces cell apoptosis. Randialic acid A (Pomolic acid) has a potential for the treatment of prostate cancer (PC) [2].

Product Specifications

CAS Number

[13849-91-7]

Product Name Alternative

Randialic acid A

UNSPSC

12352211

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pomolic-acid.html

Purity

99.97

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

OC([C@@]12[C@]([H])(C3=CC[C@]4([H])[C@]5(C)[C@@]([H])(CC[C@]4([C@@]3(CC2)C)C)C([C@H](CC5)O)(C)C)[C@]([C@@H](CC1)C)(C)O)=O

Molecular Formula

C30H48O4

Molecular Weight

472.70

References & Citations

[1]Guimarães LPTP, et al. Pomolic acid induces apoptosis and inhibits multidrug resistance protein MRP1 and migration in glioblastoma cells.Oncol Rep. 2017 Oct;38 (4) :2525-2534.|[2]Park JH, et al.Pomolic Acid Ameliorates Fibroblast Activation and Renal Interstitial Fibrosis through Inhibition of SMAD-STAT Signaling Pathways.Molecules. 2018 Sep 3;23 (9) . pii: E2236.