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3'-Methoxydaidzein

3'-Methoxydaidzein is a isoflavone and a Sodium Channel inhibitor. 3'-Methoxydaidzein inhibits subtypes NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM, and 505 nM, respectively. 3'-Methoxydaidzein exerts analgesic activity by inhibiting voltage-gated sodium channels[1].

Product Specifications

CAS Number

[21913-98-4]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Sodium Channel

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/3-methoxydaidzein.html

Purity

99.67

Smiles

O=C1C(C2=CC=C(O)C(OC)=C2)=COC3=CC(O)=CC=C13

Molecular Formula

C16H12O5

Molecular Weight

284.27

Precautions

H315, H319

References & Citations

[1]Xu RJ, et al. 3'-Methoxydaidzein exerts analgesic activity by inhibiting voltage-gated sodium channels. Chin J Nat Med. 2019 Jun;17 (6) :413-423.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Nav1.3; Nav1.7; Nav1.8

Available Sizes

Curated Selection

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