3'-Methoxydaidzein
3'-Methoxydaidzein is a isoflavone and a Sodium Channel inhibitor. 3'-Methoxydaidzein inhibits subtypes NaV1.7, NaV1.8 and NaV1.3 with IC50 of 181 nM, 397 nM, and 505 nM, respectively. 3'-Methoxydaidzein exerts analgesic activity by inhibiting voltage-gated sodium channels[1].
Product Specifications
CAS Number
[21913-98-4]
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Sodium Channel
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/3-methoxydaidzein.html
Purity
99.67
Smiles
O=C1C(C2=CC=C(O)C(OC)=C2)=COC3=CC(O)=CC=C13
Molecular Formula
C16H12O5
Molecular Weight
284.27
Precautions
H315, H319
References & Citations
[1]Xu RJ, et al. 3'-Methoxydaidzein exerts analgesic activity by inhibiting voltage-gated sodium channels. Chin J Nat Med. 2019 Jun;17 (6) :413-423.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Nav1.3; Nav1.7; Nav1.8
Available Sizes
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