TBK1/IKKε-IN-2
TBK1/IKKε-IN-2 is a dual TBK1 and IKKε inhibitor.
Product Specifications
CAS Number
[1292310-49-6]
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
IKK
Type
Reference compound
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/IKK_epsilon_-IN-1.html
Purity
98.62
Solubility
DMSO : 21.5 mg/mL (ultrasonic; warming)
Smiles
N#CC1=CC(C2=NC(NC3=CC=C(N4CCOCC4)C=C3)=NC=C2)=CC=C1OC5CCOCC5
Molecular Formula
C26H27N5O3
Molecular Weight
457.52
Precautions
H315, H319, H320
References & Citations
[1]Muvaffak A, et al. Evaluating TBK1 as a therapeutic target in cancers with activated IRF3. Mol Cancer Res. 2014 Jul;12 (7) :1055-66.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IKKε; TBK1
Available Sizes
Curated Selection
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