Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

TNIK-IN-9

TNIK-IN-9 (Compound 54) is a selective and potent NIK inhibitor, with an IC50 of 1.27 nM. TNIK-IN-9 can inhibit pro-inflammatory cytokines and nitric oxide production. TNIK-IN-9 exhibits significant anti-inflammatory effects, improved mortality, and hepatoprotective effects in sepsis models[1].

Product Specifications

UNSPSC

12352005

Target

NF-κB

Type

Reference compound

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/tnik-in-9.html

Solubility

10 mM in DMSO

Smiles

O[C@@](C1=NC=CS1)(C#CC2=NN3C(N(CCC3)C4=CC=NC(NC5=CC6=C(C=C5)OCO6)=N4)=C2)C

Molecular Formula

C24H21N7O3S

Molecular Weight

487.53

References & Citations

[1]Zhang N, et al. Design, Synthesis, and Biological Evaluation of a Novel NIK Inhibitor with Anti-Inflammatory and Hepatoprotective Effects for Sepsis Treatment. J Med Chem. 2024 Apr 11;67 (7) :5617-5641.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

5-Hydroxyquinoline-3-carboxylic Acid Hydrochloride
TRC-H876740-50MG 50 mg

5-Hydroxyquinoline-3-carboxylic Acid Hydrochloride

Sign In for Pricing
View Details
KCNE3 Rabbit Polyclonal Antibody
TA370544 100 µL

KCNE3 Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Cyanine 5.5 alkyne [equivalent to Cy5.5® alkyne]
179-AAT 1 mg

Cyanine 5.5 alkyne [equivalent to Cy5.5® alkyne]

Sign In for Pricing
View Details
Dysadherin (FXYD5) (NM_001164605) Human Over-expression Lysate
LC431776 20 µg

Dysadherin (FXYD5) (NM_001164605) Human Over-expression Lysate

Sign In for Pricing
View Details
Human HNRPLL (HNRNPLL) activation kit by CRISPRa
GA114248 1 Kit

Human HNRPLL (HNRNPLL) activation kit by CRISPRa

Sign In for Pricing
View Details
Recombinant IL1RAP Antibody
RC-5761-01 50 μL

Recombinant IL1RAP Antibody

Sign In for Pricing
View Details