Betaxolol
Betaxolol is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma.
Product Specifications
CAS Number
[63659-18-7]
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Betaxolol.html
Purity
99.76
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic)
Smiles
OC(CNC(C)C)COC1=CC=C(CCOCC2CC2)C=C1
Molecular Formula
C18H29NO3
Molecular Weight
307.43
Precautions
H315, H319, H320
References & Citations
[1]Rudoy, C.A. and E.J. Van Bockstaele, Betaxolol, a selective beta (1) -adrenergic receptor antagonist, diminishes anxiety-like behavior during early withdrawal from chronic cocaine administration in rats. Prog Neuropsychopharmacol Biol Psychiatry, 2007. 31 (5) : p. 1119-29.|[2]Lesar, T.S., Comparison of ophthalmic beta-blocking agents. Clin Pharm, 1987. 6 (6) : p. 451-63.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
Biomacromolecules. 2025 Dec 8;26 (12) :8726-8738.|Chirality. 2018 Nov;30 (11) :1195-1205.|J Pharm Biomed Anal. 2021 Feb 20:195:113870.|Missouri University of Science and Technology. 2025.|Neuron. 2025 Jun 18;113 (12) :1983-1997.e7.|ACS Biomater Sci Eng. 2022 Nov 14;8 (11) :4850-4862.|Cell Rep Methods. 2023 Oct 23;3 (10) :100599.|Invest Ophthalmol Vis Sci. 2025 Jun 2;66 (6) :13.
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