PROTAC eDHFR Degrader-1

PROTAC eDHFR Degrader-1 is a PROTAC that is effective degradation of eDHFR-YFP, various POIs-including YFP and Luciferase[1].

Product Specifications

CAS Number

[2849442-92-6]

UNSPSC

12352005

Target

PROTACs

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/protac-edhfr-degrader-1.html

Purity

98.09

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

NC1=C(CC2=CC(OC)=C(OCCCC(NCCOCCOCCNC3=CC=CC(C(N4C5CCC(NC5=O)=O)=O)=C3C4=O)=O)C(OC)=C2)C=NC(N)=N1

Molecular Formula

C36H44N8O10

Molecular Weight

748.78

References & Citations

[1]Jean M. Etersque, Regulation of eDHFR-tagged proteins with trimethoprim PROTACs.Nat Commun. 2023; 14: 7071.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP2-54451AF405 100 µL

Mouse Monoclonal PIP Antibody (PIP/1571) [Alexa Fluor 405]

Ask

View Details

GTR15311707 1 Vial

Lentiviral human CCDC25 shRNA (UAS) - Lentiviral human CCDC25 shRNA (UAS, iRFP) plasmid

Ask

View Details

RC219032L4V 200 µL

TRMT1 (TRMU) (NM_018006) Human Tagged ORF Clone Lentiviral Particle

Ask

View Details

MBS7055192 Inquire

Recombinant Mouse Potassium channel subfamily K member 4 (Kcnk4), partial

Ask

View Details