Daurinoline

Daurinoline is an alkaloid that can be isolated from the roots of Menispermum dauricum. Daurinoline may be a potential anti-tumor agent or chemosensitizer for chemo-resistant NSCLC research[1].

Product Specifications

CAS Number

2831-75-6

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/daurinoline.html

Solubility

10 mM in DMSO

Smiles

OC1=CC2=C([C@@H](CC3=CC=C(OC4=CC(C[C@H]5N(C)CCC6=C5C=C(OC)C(OC)=C6)=CC=C4O)C=C3)N(C)CC2)C=C1OC

Molecular Formula

C37H42N2O6

Molecular Weight

610.74

References & Citations

[1]Dan-Dan Li, et al. Daurinoline suppressed the migration and invasion of chemo-resistant human non-small cell lung cancer cells by reversing EMT and Notch-1 and sensitized the cells to Taxol. Environ Toxicol Pharmacol. 2019 Feb;66:109-115.