β-Amyrone

β-Amyrone (β-Amyron) is a triterpene compound which has anti-inflammatory activity through inhibiting the expression of COX-2. β-Amyrone has antifungal activity , as well as antiviral activity against Chikungunya virus. β-Amyrone also inhibits α-glucosidase and acetylcholinesterase (AChE) activity. β-Amyrone can be used in the research of disease like inflammation, infection, and obesity[1][2][3][4].

Product Specifications

CAS Number

[638-97-1]

Product Name Alternative

β-Amyron

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

CHIKV; COX; Fungal; PPAR

Type

Natural Products

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Infection; Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/β-amyrone.html

Purity

99.87

Solubility

Ethanol : 12.5 mg/mL (ultrasonic)

Smiles

C[C@]12[C@]3(C([C@@]4([H])[C@@](CC3)(CCC(C)(C4)C)C)=CC[C@]1([H])[C@@]5([C@@](C(C)(C(CC5)=O)C)([H])CC2)C)C

Molecular Formula

C30H48O

Molecular Weight

424.70

Precautions

H302, H315, H319, H335

References & Citations

[1]Patrícia D O de Almeida, et al. Anti-Inflammatory Activity of Triterpenes Isolated from Protium paniculatum Oil-Resins. Evid Based Complement Alternat Med. 2015;2015:293768.|[2]Mélanie Bourjot, et al. Chemical constituents of Anacolosa pervilleana and their antiviral activities. Fitoterapia. 2012 Sep;83 (6) :1076-80. |[3]Ki-Kwang Oh, et al. Elucidating Drug-Like Compounds and Potential Mechanisms of Corn Silk (Stigma Maydis) against Obesity: A Network Pharmacology Study. Curr Issues Mol Biol. 2021 Nov 6;43 (3) :1906-1936. |[4]Ata A, et al. Chemical constituents of Drypetes gossweileri and their enzyme inhibitory and anti-fungal activities. Phytochemistry Letters, 2011, 4 (1) : 34-37.