Recombinant Human B7-H3 Protein

<strong>Recombinant Human B7-H3 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2019256_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 48 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> 4Ig-B7-H3 Protein, Human; B7-H3 Protein, Human; B7H3 Protein, Human; B7RP-2 Protein, Human; PSEC0249 Protein, Human; UNQ309/PRO352 Protein, Human_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Li L, Nian S, Liu Q, Zhang B, Jimu W, Li C, Huang Z, Hu Q, Huang Y, Yuan Q. Fully human anti-B7-H3 recombinant antibodies inhibited tumor growth by increasing T cell infiltration Int Immunopharmacol. 2024 May 10;132:111926._x000D_ 2: Wang R, Ma Y, Zhan S, Zhang G, Cao L, Zhang X, Shi T, Chen W. B7-H3 promotes colorectal cancer angiogenesis through activating the NF-κB pathway to induce VEGFA expression Cell Death Dis. 2020 Jan 23;11(1):55._x000D_ 3: Feng P, Zhang H, Zhang Z, Dai X, Mao T, Fan Y, Xie X, Wen H, Yu P, Hu Y, Yan R. The interaction of MMP-2/B7-H3 in human osteoporosis Clin Immunol. 2016 Jan;162:118-24._x000D_ 4: Zhang GB, Chen YJ, Shi Q, Ma HB, Ge Y, Wang Q, Jiang Z, Xu Y, Zhang XG. Human recombinant B7-H3 expressed in E. coli enhances T lymphocyte proliferation and IL-10 secretion in vitro Acta Biochim Biophys Sin (Shanghai). 2004 Jun;36(6):430-6._x000D_ 5: Liu Z, Zhang W, Phillips JB, Arora R, McClellan S, Li J, Kim JH, Sobol RW, Tan M. Immunoregulatory protein B7-H3 regulates cancer stem cell enrichment and drug resistance through MVP-mediated MEK activation Oncogene. 2019 Jan;38(1):88-102._x000D_ 6: Shi J, Zhang DL, Cui ZC, Wang HM. Preparation and application of a novel monoclonal antibody specific for human B7-H3 Mol Med Rep. 2016 Jul;14(1):943-8._x000D_ 7: Zhang C, Chen Y, Li F, Yang M, Meng F, Zhang Y, Chen W, Wang W. B7-H3 is spliced by SRSF3 in colorectal cancer Cancer Immunol Immunother. 2021 Feb;70(2):311-321._x000D_ 8: Olive D. [Lymphocyte coreceptors] Med Sci (Paris). 2006 Dec;22(12):1069-74._x000D_ 9: Feng R, Wang R, Hong J, Dower CM, Croix BS, Ho M. Isolation of rabbit single domain antibodies to B7-H3 via protein immunization and phage display Antib Ther. 2020 Jan;3(1):10-17._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/32422527">10: Xu Y, Xiao Y, Luo C, Liu Q, Wei A, Yang Y, Zhao L, Wang Y. Blocking PD-1/PD-L1 by an ADCC enhanced anti-B7-H3/PD-1 fusion protein engages immune activation and cytotoxicity Int Immunopharmacol. 2020 Jul;84:106584. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant Human B7-H3 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>