Asymmetric dimethylarginine

Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS), and functions as a marker of endothelial dysfunction in a number of pathological states.

Product Specifications

CAS Number

[30315-93-6]

Product Name Alternative

NG, NG-Dimethylarginine

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; NO Synthase

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/Asymmetric_dimethylarginine.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (adjust pH to 2-3 with HCl) |H2O : 100 mg/mL (ultrasonic)

Smiles

CN(C)C(NCCC[C@H](N)C(O)=O)=N

Molecular Formula

C8H18N4O2

Molecular Weight

202.25

Precautions

H302, H315, H319, H335

References & Citations

[1]Hudson CL, et al. The cardiovascular risk marker asymmetric dimethylarginine is elevated in asymptomatic, untreated HIV-1 infection and correlates with markers of immune activation and disease progression. Ann Clin Biochem. 2014 Sep;51 (Pt 5) :568-75.