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VEGFR-2-IN-42

VEGFR-2-IN-42 (compound 8c) is a potent VEGFR-2 inhibitor. VEGFR-2-IN-42 shows anti-proliferative effect against MCF7 cells with the IC50 of 25 µM[1].

Product Specifications

UNSPSC

12352005

Target

VEGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/vegfr-2-in-42.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=CC=C(C)C=C1)NC2=NN=C(SC3=C4C=C([N+]([O-])=O)C=CC4=NC=N3)S2

Molecular Formula

C18H13N7O3S2

Molecular Weight

439.47

References & Citations

[1]Masoudinia S, et al. Novel quinazolines bearing 1,3,4-thiadiazole-aryl urea derivative as anticancer agents: design, synthesis, molecular docking, DFT and bioactivity evaluations. BMC Chem. 2024;18 (1) :30. Published 2024 Feb 12.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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