VEGFR-2-IN-42
VEGFR-2-IN-42 (compound 8c) is a potent VEGFR-2 inhibitor. VEGFR-2-IN-42 shows anti-proliferative effect against MCF7 cells with the IC50 of 25 µM[1].
Product Specifications
UNSPSC
12352005
Target
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vegfr-2-in-42.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(C)C=C1)NC2=NN=C(SC3=C4C=C([N+]([O-])=O)C=CC4=NC=N3)S2
Molecular Formula
C18H13N7O3S2
Molecular Weight
439.47
References & Citations
[1]Masoudinia S, et al. Novel quinazolines bearing 1,3,4-thiadiazole-aryl urea derivative as anticancer agents: design, synthesis, molecular docking, DFT and bioactivity evaluations. BMC Chem. 2024;18 (1) :30. Published 2024 Feb 12.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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