Kir4.1 rabbit pAb

This gene encodes a member of the inward rectifier-type potassium channel family, characterized by having a greater tendency to allow potassium to flow into, rather than out of, a cell. The encoded protein may form a heterodimer with another potassium channel protein and may be responsible for the potassium buffering action of glial cells in the brain. Mutations in this gene have been associated with seizure susceptibility of common idiopathic generalized epilepsy syndromes. [provided by RefSeq, Jul 2008],

Product Specifications

Background

UniProt

P78508

Swiss Prot

P78508

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human Kir4.1 AA range: 160-240

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Membrane ; Multi-pass membrane protein. Basolateral cell membrane . In kidney distal convoluted tubules, located in the basolateral membrane where it colocalizes with KCNJ16. .

Other Product Names

ATP-sensitive inward rectifier potassium channel 10 (ATP-dependent inwardly rectifying potassium channel Kir4.1; Inward rectifier K (+) channel Kir1.2; Potassium channel, inwardly rectifying subfamily J member 10)