PEG2000-DMPE
Product Specifications
UNSPSC Description
PEG2000-DMPE can be used to synthsis a LNP. PEG2000-DMPE enhances the entrapment efficiency depending on the increasing portion in the liposome. The optimal formulation for animal study is that DMPC/PEG2000-DMPE/CH=50/5/45 at the weight ratio of drug/lipid=1/20[1].
Target Antigen
Liposome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/peg2000-dmpe.html
Purity
95.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCCCCCCCCCCCCC(O[C@](COP(OCCNC(OCCOC)=O)(O)=O)([H])COC(CCCCCCCCCCCCC)=O)=O
Molecular Weight
2676.25
References & Citations
[1]Han I, et al. Enhanced antitumor activity [correction for activitiy] of trans(+/-)-1,2-diaminocyclo- hexaneglutamatoplatinum(II) formulated with stealth liposome. Bioorg Med Chem. 2003 Dec 1;11(24):5443-7.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-112768/PEG2000-DMPE-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-112768/PEG2000-DMPE-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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