Isoliquiritin apioside
Product Specifications
UNSPSC Description
Isoliquiritin apioside significantly decreases PMA-induced increases in MMP9 activities and suppresses PMA-induced activation of MAPK and NF-κB. Isoliquiritin apioside auppresseses invasiveness and angiogenesis of cancer cells and endothelial cells[1].
Target Antigen
MMP; NF-κB; p38 MAPK
Type
Natural Products
Related Pathways
MAPK/ERK Pathway;Metabolic Enzyme/Protease;NF-κB
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/isoliquiritin-apioside.html
Purity
99.87
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(C1=C(C=C(O)C=C1)O)/C=C/C(C=C2)=CC=C2O[C@H](O[C@H](CO)[C@@H](O)[C@@H]3O)[C@]3([H])O[C@H]4[C@@H]([C@](CO)(O)CO4)O
Molecular Weight
550.51
References & Citations
[1]Kim A1, et al. Isoliquiritin Apioside Suppresses in vitro Invasiveness and Angiogenesis of Cancer Cells and Endothelial Cells.Front Pharmacol. 2018 Dec 10;9:1455.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N2497/Isoliquiritin-apioside-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N2497/Isoliquiritin-apioside-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
120926-46-7
Available Sizes
Curated Selection
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