Kansuinine E
Kansuinine E is a plant-derived nitric oxide inhibitor (IC50=6.3 μM) . Kansuinine E belongs to jatrophane-type diterpenoids and is isolated from the roots of E. kansui[1].
Product Specifications
CAS Number
672945-84-5
UNSPSC
12352005
Target
NO Synthase
Type
Natural Products
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/kansuinine-e.html
Solubility
10 mM in DMSO
Smiles
C[C@H]1C[C@@]2(OC(C)=O)[C@@H]([C@@H](OC(C)=O)C([C@H](OC(C)=O)[C@@H](OC(C3=CC=CC=C3)=O)[C@@H](OC(C4=CN=CC=C4)=O)C(C)(C)[C@@H]5[C@H]([C@@H](C)C2=O)O5)=C)[C@H]1OC(C)=O
Molecular Formula
C41H47NO14
Molecular Weight
777.81
References & Citations
[1]Lee JW, et al. Jatrophane and ingenane-type diterpenoids from Euphorbia kansui inhibit the LPS-induced NO production in RAW 264.7 cells. Bioorg Med Chem Lett. 2016;26 (14) :3351-3354.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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