C6 D-Threo Ceramide (d18:1/6:0)
C6 D-Threo Ceramide (d18:1/6:0) is a bioactive sphingolipid and cell-permeable analog of ceramides. C6 D-Threo Ceramide (d18:1/6:0) enhances IL-4 production induced by Phorbol 12-myristate 13-acetate in EL4 T cells[1][2].
Product Specifications
CAS Number
189894-79-9
UNSPSC
12352211
Target
Interleukin Related; Liposome
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/c6-d-threo-ceramide-d18-1-6-0.html
Smiles
OC[C@@H](NC(CCCCC)=O)[C@@H](/C=C/CCCCCCCCCCCCC)O
Molecular Formula
C24H47NO3
Molecular Weight
397.63
References & Citations
[1]Park J, et al. Inhibitory activity of a ceramide library on interleukin-4 production from activated T cells. Bioorg Med Chem. 2005 Apr 1;13 (7) :2589-95.|[2]Irie F, et al. Application of exogenous ceramide to cultured rat spinal motoneurons promotes survival or death by regulation of apoptosis depending on its concentrations. J Neurosci Res. 1998 Nov 15;54 (4) :475-85.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-4
Frequently Asked Questions
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