B7-1/CD80, Rat (HEK293, His)

B7-1/CD80 Protein, Rat (HEK293, His) is not only expressed on APCs, but also is expressed on T cells. B7-1:PD-L1 interaction can inhibit T cell proliferation and cytokine production[1].

VGLFQISSGI VGQVSKSVRE KALLSCDYKF CSEEQSIHRI YWQKHDKMVL SVISGVPEVW P EYKNRTVY DIANNYSFSL LGLILSDRGT YTCVVQRYEG ESYVVKHLTT VELSVRADFP TPNITESGNP SADIKRITCF ASGGFPKPRL SWLENGRELN GINTTISQDP ESELYTISSQ LDFNTTYDHF IDCFIEYGDA HVSQNFTWVK PPEDPPDEKQ HHHHHH

[1]Manish J Butte, et al. Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses. Immunity. 2007 Jul;27(1):111-22.