Chloropyramine hydrochloride
Chloropyramine hydrochloride is a histamine receptor H1 antagonist which can also inhibit the biochemical function of VEGFR-3 and FAK.
Product Specifications
CAS Number
6170-42-9
UNSPSC
12352005
Hazard Statement
H302, H312, H315, H319, H332
Target
FAK; Histamine Receptor; VEGFR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Chloropyramine_hydrochloride.html
Purity
99.64
Solubility
DMSO : 30 mg/mL (ultrasonic; warming) |H2O : 100 mg/mL (ultrasonic)
Smiles
CN(C)CCN(CC1=CC=C(Cl)C=C1)C2=NC=CC=C2.[H]Cl
Molecular Formula
C16H21Cl2N3
Molecular Weight
326.26
Precautions
H302, H312, H315, H319, H332
References & Citations
[1]Kurenova EV, et al. Small molecule chloropyramine hydrochloride (C4) targets the binding site of focal adhesion kinase and vascular endothelial growth factor receptor 3 and suppresses breast cancer growth in vivo. J Med Chem. 2009 Aug 13;52 (15) :4716-24.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
H1 Receptor; VEGFR3/Flt-4
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC400204-100 1x 100 µL
Complement C4d (C4D204), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC681820-500 1x 500 µL
Ep-CAM / CD326 (Epithelial Marker) (rVU-1D9), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400158-100 1x 100 µL
Cytokeratin 17 (E3), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880008-500 1x 500 µL
MAGE A1 (MA454), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC472478-100 1x 100 µL
CD3e (T-Cell Marker) (C3e/2478), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details