FAK-IN-10
Product Specifications
UNSPSC Description
FAK-IN-10 is an inhibitor of FAK with an IC50 of 76.3 μM. FAK-IN-10 exhibits antitumor activity against MCF-7 and A431 cell lines with IC50s of 4.23 and 0.78 μM,respectively[1].
Target Antigen
FAK
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fak-in-10.html
Solubility
DMSO : 20 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(CSC1=NN=C(C2=CC=NC=C2)O1)C3=CC=C(C=C3)Br
Molecular Weight
376.23
References & Citations
[1]Zhang LR, et al. Synthesis, biological evaluation and molecular docking studies of novel 2-(1,3,4-oxadiazol-2-ylthio)-1-phenylethanone derivatives. Bioorg Med Chem. 2012 Jun 1;20(11):3615-21.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153697/FAK-IN-10-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153697/FAK-IN-10-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
491839-65-7
Available Sizes
Curated Selection
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