SR94
SR94, a SR17 derivative, is a SIRT2 inhibitor that contains an arbitrary 6-member ring and different R2 groups. SR94 is promising for research of cancer, ischemia-reperfusion and neurodegenerative diseases[1].
Product Specifications
CAS Number
550301-63-8
UNSPSC
12352005
Target
Sirtuin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sr94.html
Smiles
O=C(CSC1=NC(N(CC2=CC=CC=C2)C3=CC=CC=C43)=C4N=N1)NC5=C(OC)C=CC=C5
Molecular Formula
C25H21N5O2S
Molecular Weight
455.53
References & Citations
[1]Huang S, et al. Discovery of New SIRT2 Inhibitors by Utilizing a Consensus Docking/Scoring Strategy and Structure-Activity Relationship Analysis. J Chem Inf Model. 2017 Apr 24;57 (4) :669-679.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SIRT2
Available Sizes
Frequently Asked Questions
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