Ranitidine
Ranitidine is a potent, selective and orally active histamine H2-receptor antagonist that inhibits gastric secretion. Ranitidine antagonizes Histamine -induced increases of the guinea-pig isolated rat atrium and Histamine-induced relaxations of the rat isolated uterine horn, with pA2 values of 7.2 and 6.95, respectively. Ranitidine inhibits breast tumor development and spread in mice[1][2].
Product Specifications
CAS Number
66357-35-5
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ranitidine.html
Concentration
10mM
Purity
99.9
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=[N+](/C=C(NC)/NCCSCC1=CC=C(CN(C)C)O1)[O-]
Molecular Formula
C13H22N4O3S
Molecular Weight
314.40
Precautions
H315, H319, H320
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
H2 Receptor
Available Sizes
Frequently Asked Questions
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