Ranitidine
Ranitidine is a potent, selective and orally active histamine H2-receptor antagonist that inhibits gastric secretion. Ranitidine antagonizes Histamine -induced increases of the guinea-pig isolated rat atrium and Histamine-induced relaxations of the rat isolated uterine horn, with pA2 values of 7.2 and 6.95, respectively. Ranitidine inhibits breast tumor development and spread in mice[1][2].
Product Specifications
CAS Number
66357-35-5
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ranitidine.html
Concentration
10mM
Purity
99.9
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=[N+](/C=C(NC)/NCCSCC1=CC=C(CN(C)C)O1)[O-]
Molecular Formula
C13H22N4O3S
Molecular Weight
314.40
Precautions
H315, H319, H320
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
H2 Receptor
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Mouse Inactive dipeptidyl peptidase 10, DPP10 ELISA Kit
Mouse Inactive dipeptidyl peptidase 10, DPP10 ELISA Kit
Mouse Inactive dipeptidyl peptidase 10, DPP10 ELISA Kit