Tradipitant
Tradipitant (VLY-686) is a neurokinin-1 (NK-1) antagonist.
Product Specifications
CAS Number
[622370-35-8]
Product Name Alternative
VLY-686; LY686017
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Neurokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Infection; Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Tradipitant.html
Purity
99.66
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CN=C1C2=C(C3=CC=NC=C3)N(CC4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)N=N2)C5=CC=CC=C5Cl
Molecular Formula
C28H16ClF6N5O
Molecular Weight
587.90
Precautions
H302, H315, H319, H335
References & Citations
[1]Gackenheimer SL, et al. In vitro and ex vivo autoradiography of the NK-1 antagonist [3H]-LY686017 in Guinea pig brain. Neuropeptides. 2011 Apr;45 (2) :157-64.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Curated Selection
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