Isothiafludine

Isothiafludine is an orally active non-nucleosidic anti-HBV compound. Isothiafludine inhibits hepatitis B virus replication by blocking pregenomic RNA encapsidation[1].

Product Specifications

CAS Number

[960527-22-4]

Product Name Alternative

NZ-4

UNSPSC

12352005

Target

HBV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/isothiafludine.html

Purity

99.87

Solubility

10 mM in DMSO

Smiles

O=C(C1=C(CC(C)C)SC(C2=NC=CS2)=N1)NCC3=CC=C(F)C=C3

Molecular Formula

C18H18FN3OS2

Molecular Weight

375.48

References & Citations

[1]Yang L, et al. Isothiafludine, a novel non-nucleoside compound, inhibits hepatitis B virus replication through blocking pregenomic RNA encapsidation. Acta Pharmacol Sin. 2014 Mar;35 (3) :410-8.