Isothiafludine
Isothiafludine is an orally active non-nucleosidic anti-HBV compound. Isothiafludine inhibits hepatitis B virus replication by blocking pregenomic RNA encapsidation[1].
Product Specifications
CAS Number
[960527-22-4]
Product Name Alternative
NZ-4
UNSPSC
12352005
Target
HBV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/isothiafludine.html
Purity
99.87
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(CC(C)C)SC(C2=NC=CS2)=N1)NCC3=CC=C(F)C=C3
Molecular Formula
C18H18FN3OS2
Molecular Weight
375.48
References & Citations
[1]Yang L, et al. Isothiafludine, a novel non-nucleoside compound, inhibits hepatitis B virus replication through blocking pregenomic RNA encapsidation. Acta Pharmacol Sin. 2014 Mar;35 (3) :410-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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