DMS-612
DMS-612 (NSC-281612) is an alkylating agent with anti-renal cell carcinoma activity. DMS-612 can be used in cancer research[1].
Product Specifications
CAS Number
[56967-08-9]
Product Name Alternative
NSC-281612
UNSPSC
12352005
Target
DNA Alkylator/Crosslinker
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dms-612.html
Solubility
10 mM in DMSO
Smiles
O=CC1=CC=C(N(CCOS(=O)(C)=O)CCOS(=O)(C)=O)C=C1C
Molecular Formula
C14H21NO7S2
Molecular Weight
379.45
References & Citations
[1]Parise RA, et al. Formation of active products of benzaldehyde dimethane sulfonate (NSC 281612, DMS612) in human blood and plasma and their activity against renal cell carcinoma lines. Cancer Chemother Pharmacol. 2013 Jan;71 (1) :73-83. doi: 10.1007/s00280-012-1980-1. Epub 2012 Oct 5.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-19412/DMS-612-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-19412/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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