FQ

FQ is a tyrosinase inhibitor that effectively inhibits the diphenolase activity of mushroom tyrosinase (IC50=120 μM) . FQ can be used in the study of pigmentation[1].

Product Specifications

CAS Number

[190838-76-7]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Tyrosinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/fq.html

Smiles

O=C1N=C(NC2=C1C=CC=C2)C3=CC=C(C=C3)F

Molecular Formula

C14H9FN2O

Molecular Weight

240.23

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Wang R, et al. 2- (4-Fluorophenyl) -quinazolin-4 (3H) -one as a novel tyrosinase inhibitor: Synthesis, inhibitory activity, and mechanism. Bioorg Med Chem. 2016 Oct 1;24 (19) :4620-4625.