Travoprost

Travoprost (Fluprostenol isopropyl ester), an isopropyl ester proagent, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension[1].

Product Specifications

CAS Number

[157283-68-6]

Product Name Alternative

Fluprostenol isopropyl ester; AL6221; Flu-Ipr

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Field of Research

Endocrinology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/travoprost.html

Purity

99.99

Solubility

DMSO : ≥ 41.67 mg/mL|Ethanol : 60 mg/mL (ultrasonic)

Smiles

O=C(OC(C)C)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)COC2=CC=CC(C(F)(F)F)=C2)[C@H](O)C[C@@H]1O

Molecular Formula

C26H35F3O6

Molecular Weight

500.55

Precautions

H302, H315, H319, H335

References & Citations

[1]M R Hellberg, et al. Preclinical efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist. J Ocul Pharmacol Ther. 2001 Oct;17 (5) :421-32.