Fluphenazine decanoate (dihydrochloride)

Fluphenazine decanoate dihydrochloride is a dopamine D2 receptor inhibitor, is a long-acting phenothiazine neuroleptic. Fluphenazine can be used for schizophrenia research[1][2][3].

Product Specifications

CAS Number

[2376-65-0]

UNSPSC

12352005

Hazard Statement

H301

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/fluphenazine-decanoate-dihydrochloride.html

Solubility

10 mM in DMSO

Smiles

CCCCCCCCCC(OCCN1CCN(CCCN2C3=C(C=CC=C3)SC4=CC=C(C(F)(F)F)C=C24)CC1)=O.[H]Cl.[H]Cl

Molecular Formula

C32H46Cl2F3N3O2S

Molecular Weight

664.69

Precautions

P264-P270-P330-P405-P501

References & Citations

[2]Lifshitz K, et al. Effects of dopamine agonists on Cebus apella monkeys with previous long-term exposure to fluphenazine. Biol Psychiatry. 1997 Mar 15;41 (6) :657-67.|[3]Stoessl AJ, et al. Chronic neuroleptic-induced mouth movements in the rat: suppression by CCK and selective dopamine D1 and D2 receptor antagonists. Psychopharmacology (Berl) . 1989;98 (3) :372-9. |[4]Gill-Sharma MK, et al. Antifertility effects of fluphenazine in adult male rats. J Endocrinol Invest. 2003 Apr;26 (4) :316-26. |[1]Goodwin DG, et al. Evaluation of five antischizophrenic agents against Toxoplasma gondii in human cell cultures. J Parasitol. 2011 Feb;97 (1) :148-51.