Plecstatin-1
Plecstatin-1 is a potent organoruthenium anti-cancer agent[1]. Plecstatin-1 selectively targets plectin (a scaffold protein and cytolinker) in tumour spheroids[1].
Product Specifications
CAS Number
2119725-22-1
UNSPSC
12352300
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/plecstatin-1.html
Solubility
10 mM in DMSO
Smiles
[Cl-][Ru+2]12345([CH]6=[CH]47)([N]8=CC=CC=C8C(NC(C=C9)=CC=C9F)=[S]5)[C]6(C(C)C)=[CH]1[CH]2=[C]37C.[Cl-]
Molecular Formula
C22H23Cl2FN2RuS
Molecular Weight
538.47
References & Citations
[1]Debora Wernitznig, et al. Plecstatin-1 induces an immunogenic cell death signature in colorectal tumour spheroids. Metallomics. 2020 Dec 23;12 (12) :2121-2133.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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