Tebuconazole
Tebuconazole is an orally active agricultural azole fungicide which can also inhibit CYP51 with IC50s of 0.9 and 1.3 μM for Candida albicans CYP51 (CaCYP51) and truncated Homo sapiens CYP51 (Δ60HsCYP51), respectively. Tebuconazole induces lipid accumulation and oxidative stress in HepG2 Cells. Tebuconazole decreases MAC-T cells viability and proliferation, induces ER-stress-mediated apoptosis and increases oxidative stress levels in MAC-T cells[1][2][3][4][5][6].
Product Specifications
CAS Number
107534-96-3
UNSPSC
12352005
Hazard Statement
H302, H361, H400, H410
Target
Apoptosis; Cytochrome P450; Fungal
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Tebuconazole.html
Purity
99.63
Solubility
DMSO : ≥ 50 mg/mL|H2O : < 0.1 mg/mL
Smiles
CC(C)(C)C(O)(CCC1=CC=C(Cl)C=C1)CN2C=NC=N2
Molecular Formula
C16H22ClN3O
Molecular Weight
307.82
Precautions
H302, H361, H400, H410
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CYP51
Available Sizes
Frequently Asked Questions
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