MC-Val-Cit-PAB-NH-C2-NH-Boc
Product Specifications
UNSPSC Description
MC-Val-Cit-PAB-NH-C2-NH-Boc is a cathepsin cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Target Antigen
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mc-val-cit-pab-nh-c2-nh-boc.html
Smiles
CC(C)(C)OC(NCCNC(OCC(C=C1)=CC=C1NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN2C(C=CC2=O)=O)=O)=O)=O)=O)=O
Molecular Weight
758.86
References & Citations
[1]Akaiwa M, et al. Synthesis and Evaluation of Linear and Macrocyclic Dolastatin 10 Analogues Containing Pyrrolidine Ring Modifications. ACS Omega. 2018;3(5):5212-5221.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-132973/MC-Val-Cit-PAB-NH-C2-NH-Boc-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-132973/MC-Val-Cit-PAB-NH-C2-NH-Boc-SDS-MedChemExpress.pdf
CAS Number
1616727-22-0
Available Sizes
Curated Selection
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