MC-Val-Cit-PAB-NH-C2-NH-Boc
MC-Val-Cit-PAB-NH-C2-NH-Boc is a cathepsin cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[1616727-22-0]
UNSPSC
12352203
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mc-val-cit-pab-nh-c2-nh-boc.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
CC(C)(C)OC(NCCNC(OCC(C=C1)=CC=C1NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN2C(C=CC2=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C36H54N8O10
Molecular Weight
758.86
References & Citations
[1]Akaiwa M, et al. Synthesis and Evaluation of Linear and Macrocyclic Dolastatin 10 Analogues Containing Pyrrolidine Ring Modifications. ACS Omega. 2018;3 (5) :5212-5221.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; Protease Cleavable Linker
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
E8078 96 Tests
Macrophage erythroblast attAChEr (MAEA) Mouse ELISA Kit
Sign In for Pricing
View Details 
LV674516 1.0 µg DNA
Cyp2d3 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA)
Sign In for Pricing
View Details 
MBS184007-01 0.01 mg
Recombinant Human Fibroblast Growth Factor Receptor 4, FGFR4
Sign In for Pricing
View Details MBS184007-02 0.05 mg
Recombinant Human Fibroblast Growth Factor Receptor 4, FGFR4
Sign In for Pricing
View Details