Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

UBCS039

UBCS039 is the first synthetic, specific Sirtuin 6 (SIRT6) activator, inducing autophagy in human tumor cells, with an EC50 of 38 μM[1].

Product Specifications

CAS Number

358721-70-7

Product Name Alternative

5-(4-Phenoxybutoxy)psoralen,ZM-211974

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Autophagy; Sirtuin

Type

Reference compound

Related Pathways

Autophagy; Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ubcs039.html

Purity

98.88

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

N12C(C(C3=CC=CN=C3)NC4=C2C=CC=C4)=CC=C1

Molecular Formula

C16H13N3

Molecular Weight

247.29

Precautions

H302, H315, H319, H335

References & Citations

[1]Weijie You, et al. Structural Basis of Sirtuin 6 Activation by Synthetic Small Molecules. Angew. Chem. Int. Ed. 2017, 56, 1007-1011.|[2]Sara Iachettini, et al. Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells. Cell Death and Disease (2018) 9:996.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

SIRT6

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Frataxin (Mitochondrial Marker) (rFXN/2124), CF647 conjugate, 0.1mg/mL
BNC473794-100 1x 100 µL

Frataxin (Mitochondrial Marker) (rFXN/2124), CF647 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
SAM domain containing protein 5 (SAMD5) (NM_001030060) Human Over-expression Lysate
LC422245 20 µg

SAM domain containing protein 5 (SAMD5) (NM_001030060) Human Over-expression Lysate

Sign In for Pricing
View Details
Hieff NGS™ Universal Library Conversion Kit
13342ES16 16 Tests

Hieff NGS™ Universal Library Conversion Kit

Sign In for Pricing
View Details
Elab Fluor® Red 780 Anti-Human CD66b Antibody[G10F5]
E-AB-F1267S-01 20 Tests

Elab Fluor® Red 780 Anti-Human CD66b Antibody[G10F5]

Sign In for Pricing
View Details
Elab Fluor® Red 780 Anti-Human CD66b Antibody[G10F5]
E-AB-F1267S-02 100 Tests

Elab Fluor® Red 780 Anti-Human CD66b Antibody[G10F5]

Sign In for Pricing
View Details
Elab Fluor® Red 780 Anti-Human CD66b Antibody[G10F5]
E-AB-F1267S-03 2x 100 Tests

Elab Fluor® Red 780 Anti-Human CD66b Antibody[G10F5]

Sign In for Pricing
View Details