Thapsigargin
Thapsigargin, an endoplasmic reticulum (ER) stress inducer, is an inhibitor of microsomal Ca2+-ATPase. Thapsigargin efficiently inhibits coronavirus (HCoV-229E, MERS-CoV, SARS-CoV-2) replication in different cell types[1][2][3][4][5].
Product Specifications
CAS Number
[67526-95-8]
UNSPSC
12352005
Hazard Statement
H315, H319, H334, H335
Target
Apoptosis; Calcium Channel; SARS-CoV
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/Thapsigargin.html
Purity
99.95
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CCCCCCCC(O[C@@H]1[C@@H](OC(/C(C)=C\C)=O)C(C)=C2[C@@]1([H])[C@@](C)(OC(C)=O)C[C@H](OC(CCC)=O)[C@@]([C@@]3(O)C)(O)[C@@]2([H])OC3=O)=O
Molecular Formula
C34H50O12
Molecular Weight
650.75
Precautions
H315, H319, H334, H335
References & Citations
2+
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
RNF38 CRISPRa sgRNA lentivector (set of three targets)(Mouse)
