Jak1 (phospho-Tyr1034/1035) rabbit pAb
This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
Product Specifications
Background
Product Name Alternative
Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)
UniProt
P23458
Swiss Prot
P23458
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized phosho peptide around human Jak1 (Tyr1034 and 1035)
Target
JAK1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Molecular Weight
132kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
132kD
Fragment
IgG
Subcellular Location
Endomembrane system; Peripheral membrane protein. Wholly intracellular, possibly membrane associated.
Other Product Names
Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)
Gene ID (Human)
3716
Available Sizes
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