BMS 695735
Product Specifications
UNSPSC Description
BMS 695735 (compound 10) is an inhibitor of IGF-1R with an IC50 value of 0.034 μM. BMS 695735 has anti-tumor activity[1].
Target Antigen
IGF-1R
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bms-695735.html
Smiles
O=C1C(C2=NC3=C(C)C=C(C4CCN(CCCF)CC4)C=C3N2)=C(NCCN5N=CC(Cl)=C5)C=CN1
Molecular Weight
512.02
References & Citations
[1]Discovery and Evaluation of 4-(2-(4-chloro-1H-pyrazol-1-yl)ethylamino)-3-(6-(1-(3-fluoropropyl)piperidin-4-yl)-4-methyl-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one (BMS-695735), an Orally Efficacious Inhibitor of Insulin-like Growth Factor-1 Receptor Kinase with Broad Spectrum in Vivo Antitumor Activity
J. Med. Chem., 2008, 51 (19), pp 5897-5900
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-14357/BMS-695735-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-14357/
Clinical Information
No Development Reported
CAS Number
1054315-48-8
Curated Selection
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