BMS 695735
BMS 695735 (compound 10) is an inhibitor of IGF-1R with an IC50 value of 0.034 μM. BMS 695735 has anti-tumor activity[1].
Product Specifications
CAS Number
[1054315-48-8]
UNSPSC
12352005
Target
IGF-1R
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bms-695735.html
Smiles
O=C1C(C2=NC3=C(C)C=C(C4CCN(CCCF)CC4)C=C3N2)=C(NCCN5N=CC(Cl)=C5)C=CN1
Molecular Formula
C26H31ClFN7O
Molecular Weight
512.02
References & Citations
[1]Discovery and Evaluation of 4- (2- (4-chloro-1H-pyrazol-1-yl) ethylamino) -3- (6- (1- (3-fluoropropyl) piperidin-4-yl) -4-methyl-1H-benzo[d]imidazol-2-yl) pyridin-2 (1H) -one (BMS-695735), an Orally Efficacious Inhibitor of Insulin-like Growth Factor-1 Receptor Kinase with Broad Spectrum in Vivo Antitumor Activity
 J. Med. Chem., 2008, 51 (19), pp 5897-5900
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-14357/BMS-695735-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-14357/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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