Anti-CD3 epsilon (activation epitope) FITC

Product Specifications

CAS Number

9007-83-4

Gene Name

[CD3E]

NCBI Gene ID

916

Reactivity

Mouse, Human

Storage Conditions

Store in the dark at 2-8 degree C. Do not freeze. Avoid prolonged exposure to light.

Specificity

The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.

Other Gene Names

[CD3E; CD3E; T3E; TCRE; IMD18; T3E]

Short Name

[CD3 epsilon]

Other Product Names

[T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; CD3e molecule; T-cell surface antigen T3/Leu-4 epsilon chain; CD_antigen: CD3e]